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ZINC FINGER E BOX BINDING HOMEOBOX 1
Descriptors Found:
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DeCS
Descriptor
English
:
Zinc Finger E-box-Binding Homeobox 1
Descriptor
Spanish
:
caja homeótica de unión a la caja E con dedos de zinc
Descriptor
Portuguese
:
Homeobox 1 de Ligação a E-box em Dedo de Zinco
Synonyms
English
:
NIL-2-A Zinc Finger Protein
TCF8 Protein
Transcription Factor 8
Zeb1 Transcription Factor
NIL 2 A Zinc Finger Protein
Transcription Factor, Zeb1
Zinc Finger E box Binding Homeobox 1
Tree Number:
D12.776.260.400.906
D12.776.260.703.800
D12.776.930.780.945
Definition
English
:
A transcription factor characterized by N-terminal and C-terminal
CYS2-HIS2 ZINC FINGERS
separated by a homeobox. It represses the expression of E-CADHERIN to induce the
EPITHELIAL-MESENCHYMAL TRANSITION
. It also represses
PROTO-ONCOGENE PROTEINS C-BCL-6
; regulates the cell type-specific expression of
SODIUM-POTASSIUM-EXCHANGING ATPASE
; and promotes neuronal differentiation.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56604
Unique Identifier:
D000071799
Occurrence in VHL
:
Similar:
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CID-10
LILACS