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DeCS
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Descriptor English:
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Ferrochelatase
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Descriptor Spanish:
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ferroquelatasa
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Descriptor Portuguese:
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Ferroquelatase
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Synonyms English:
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Protoheme Ferro-Lyase
Zinc Chelatase
Chelatase, Porphyrin-Metal
Chelatase, Zinc
Ferro-Lyase, Protoheme
Porphyrin Metal Chelatase
Protoheme Ferro Lyase
Synthetase, Heme
Heme Synthetase
Porphyrin-Metal Chelatase
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Tree Number:
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D08.811.520.500
D12.776.157.427.374.375.957
D12.776.556.579.374.375.617
D12.776.575.562
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Definition English:
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A mitochondrial enzyme found in a wide variety of cells and tissues. It is the final enzyme in the 8-enzyme biosynthetic pathway of HEME. Ferrochelatase catalyzes ferrous insertion into protoporphyrin IX to form protoheme or heme. Deficiency in this enzyme results in ERYTHROPOIETIC PROTOPORPHYRIA. |
Entry Combination - descr/qualif English:
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Ferrochelatase/deficiency use Protoporphyria, Erythropoietic
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History Note English:
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1991(1977); use LYASES 1977-1990
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Allowable Qualifiers English:
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Record Number:
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5403
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Unique Identifier:
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D005294
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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