Pesquisa sobre: CYTOCHROME P-450 CYP3A 
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Descritor Inglês:   Cytochrome P-450 CYP3A 
Descritor Espanhol:   citocromo P-450 CYP3A 
Descritor Português:   Citocromo P-450 CYP3A 
Sinônimos Inglês:   CYP3A4
CYP3A5
Cytochrome P-450 CYP3A4
Cytochrome P-450 CYP3A5
Cytochrome P-450IIIA
Cytochrome P450 3A
Cytochrome P450 3A4
Cytochrome P450 3A5
Erythromycin N-Demethylase
Taurochenodeoxycholate 6-alpha-Monooxygenase
3A5, Cytochrome P450
6-alpha-Monooxygenase, Taurochenodeoxycholate
Cytochrome P 450 CYP3A
Cytochrome P 450 CYP3A4
Cytochrome P 450 CYP3A5
Cytochrome P 450IIIA
Erythromycin N Demethylase
N-Demethylase, Erythromycin
P-450 CYP3A, Cytochrome
P-450 CYP3A4, Cytochrome
P-450 CYP3A5, Cytochrome
P-450IIIA, Cytochrome
P450 3A, Cytochrome
P450 3A5, Cytochrome
Taurochenodeoxycholate 6 alpha Monooxygenase
CYP3A  
Categoria:   D08.244.453.860.500
D08.811.682.662.582.353
D08.811.682.690.708.170.495.500
D12.776.422.220.453.860.500
Definição Inglês:   A cytochrome P-450 suptype that has specificity for a broad variety of lipophilic compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN. 
Combinados Inglês:   Cytochrome P-450 CYP3A/antagonists & inhibitors use Cytochrome P-450 CYP3A Inhibitors
 
Nota Histórica Inglês:   2006(1980) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   50572 
Identificador Único:   D051544 

Ocorrência na BVS: 		 

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