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SMOOTHENED RECEPTOR
Descriptors Found:
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DeCS
Descriptor
English
:
Smoothened Receptor
Descriptor
Spanish
:
receptor Smoothened
Descriptor
Portuguese
:
Receptor Smoothened
Synonyms
English
:
Smoothened Protein
Smoothened Receptors
Receptor, Smoothened
Receptors, Smoothened
Tree Number:
D12.776.543.750.695.017.500
D12.776.543.750.850.500.500
Definition
English
:
A frizzled-like, G-protein-coupled receptor that associates with
PATCHED RECEPTORS
to transduce signals from
HEDGEHOG PROTEINS
and initiate hedgehog signaling to
ZINC FINGER PROTEIN GLI1
. It may normally inhibit signaling in the absence of SONIC HEDGEHOG
PROTEIN binding
to PATCHED RECEPTOR-1.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
56644
Unique Identifier:
D000072086
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS