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ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY G, MEMBER 2
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DeCS
Descriptor
English
:
ATP Binding Cassette Transporter, Sub-Family G, Member 2
Descriptor
Spanish
:
transportador de casetes de unión a ATP, subfamilia G, miembro 2
Descriptor
Portuguese
:
Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP
Synonyms
English
:
ABCG2 Protein
ABCG2 Transporter
CD338 Antigen
Antigen, CD338
Tree Number:
D12.776.157.530.100.228.500
D12.776.395.550.020.457.500
D12.776.543.550.192.457.500
D12.776.543.585.100.228.500
Definition
English
:
An ATP binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of
STEROLS
, and in the
absorption
and efflux of many drugs. Its efflux activity for
ANTINEOPLASTIC AGENTS
contributes to
DRUG RESISTANCE
. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by
NEOPLASTIC STEM CELLS.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56579
Unique Identifier:
D000070997
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS